To neutralize 0.5 L of 120 mM 66930 solution, it is recommended to use 8 ml of 0.5 N HCl to adjust the pH to 8, and then dilute the HCl (e.g. 0.1 N) to titrate to pH 7.3. This approach can help avoid the drastic drop in pH.
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| Rozmiar/SKU | Dostępność | Cena netto |
|---|---|---|
100 g | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 203,00 zł |
500 g | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 587,00 zł |
Informacje o tej pozycji
203,00 zł
biological source
synthetic
Quality Segment
product line
ReagentPlus®
assay
≥99.0% (T)
form
powder
optical activity
[α]20/D −16.5±0.5°, c = 2% in H2O
autoignition temp.
~662 °F
mp
126-131 °C, 129-131.5 °C (lit.)
solubility
H2O: 0.1 g/mL, clear, colorless
anion traces
chloride (Cl-): ≤50 mg/kg, phosphate (PO43-): ≤5 mg/kg, sulfate (SO42-): ≤50 mg/kg
cation traces
Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤20 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg
SMILES string
CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI
1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1
InChI key
MBBZMMPHUWSWHV-BDVNFPICSA-N
General description
Application
- An ion exchange resin due to its high affinity and selectivity for specific ions
- A buffering agent to remove boron from an aqueous solution
Legal Information
1 of 1
Ta pozycja | |||
|---|---|---|---|
| description ReagentPlus®, ≥99.0% (T) | description 99.0-100.5% (titration) | description United States Pharmacopeia (USP) Reference Standard | description European Pharmacopoeia (EP) Reference Standard |
| biological source synthetic | biological source - | biological source - | biological source - |
| assay ≥99.0% (T) | assay 99.0-100.5% (titration) | assay - | assay - |
| solubility H2O: 0.1 g/mL, clear, colorless | solubility - | solubility - | solubility - |
| Quality Level 200 | Quality Level 200 | Quality Level - | Quality Level - |
| form powder | form powder | form - | form - |
| mp 129-131.5 °C (lit.), 126-131 °C | mp 129-131.5 °C (lit.) | mp 129-131.5 °C (lit.) | mp 129-131.5 °C (lit.) |
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Klasa składowania
11 - Combustible Solids
Co się dzieje?
WGK 1
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
PPE (środki ochrony indywidualnej)
Eyeshields, Gloves, type N95 (US)
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What is the optimal volume of HCl to use in order to achieve a pH of 7.3 when using N-Methyl-D-glucamine (P/N: 66930) in a patch clamp solution without adding any additional Na+ ions?
1 answer-
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When preparing a solution for patch clamping, what is the best optimal amount of HCL to use for ensuring that NaOH will not be required to maintain pH 7.3? F
1 answer-
The necessary amount of HCl would need to be determined by the end-user. It is recommended to record the initial pH value prior to the addition of HCl. After recording the intial pH, add small increments of HCl (1-2 mL). The molarity of the HCL must also be considered when adding incremental volumes. A 1M HCl would be considered fairly dilute. Higher concentrations would require volume adjustments. Record the pH value after 5 minutes of stirring.
For further questions or concerns, please navigate to the link https://www.sigmaaldrich.com/techservice, click on "Product Technical Inquiries" under the Products Section with all the required information so that a member of the Technical Service team can reach out to assist further. Thank you.
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