This product may be stored at room temperature. The material has not been tested for sensitivity to light at specific wavelengths. However, therapeutic products under the name Leucovorin are considered UV sensitive. Please see the link below to review a publication that may be of interest:
https://pmc.ncbi.nlm.nih.gov/articles/PMC3940680/
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F7878
Folinic acid calcium salt hydrate
analytical standard
Synonim(y):
5-Formyl-5,6,7,8-tetrahydrofolic acid calcium salt, 5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid calcium salt, 5-HCO-H4PteGlu, Calcium folinate, Citrovorum factor calcium salt, Leucovorin calcium salt
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| Rozmiar/SKU | Dostępność | Cena netto |
|---|---|---|
100 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 476,00 zł |
500 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 1550,00 zł |
1 g | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 2930,00 zł |
Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C20H21CaN7O7 · xH2O
Numer CAS:
Masa cząsteczkowa:
511.50 (anhydrous basis)
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Beilstein/REAXYS Number:
5723924
eCl@ss:
25140904
476,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Pomoc techniczna
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Pozwól nam pomócbiological source
synthetic (organic)
Quality Segment
grade
analytical standard
assay
≥90.0%
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
color
yellow to orange
mp
240-250 °C
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
[Ca++].[H]O[H].[H]C(=O)N1C(CNc2ccc(cc2)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)CNc3nc(N)nc(O)c13
InChI
1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);/q;+2/p-2/t12?,13-;/m0./s1
InChI key
KVUAALJSMIVURS-ZEDZUCNESA-L
General description
Folinic acid calcium salt hydrate is a drug, widely used for the treatment of cancer, since it can reduce toxic side effects and helps to improve drug accumulation in tumor tissues.
Application
Calcium folinate offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate. In medicine, calcium folinate is used after treatment with methotrexate to reduce the toxicity of the methotrexate. Calcium folinate is also used to enhance the cytotoxic effect of 5-fluorouracil in the treatment of cancer.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Folinic acid calcium salt hydrate has been used as a test compound to study its effects on microglia involved in neuro-inflammation using enzyme-linked immunosorbent assay (ELISA) technique.
Folinic acid calcium salt hydrate has been used as a test compound to study its effects on microglia involved in neuro-inflammation using enzyme-linked immunosorbent assay (ELISA) technique. Folinic acid calcium salt hydrate may be used as an analytical reagent for the quantification of methotrexate its metabolites in biological samples using turbulent flow chromatography with tandem mass spectrometry.
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Ta pozycja | |||
|---|---|---|---|
| description analytical standard | description BioXtra, ≥99.0% (HPLC) | description European Pharmacopoeia (EP) Reference Standard | description Pharmaceutical Secondary Standard; Certified Reference Material |
| technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) cell culture | mammalian: suitable | technique(s) liquid chromatography (LC): suitable, gas chromatography (GC): suitable | technique(s) gas chromatography (GC): suitable, HPLC: suitable |
| application(s) forensics and toxicology | application(s) cell analysis | application(s) pharmaceutical | application(s) pharmaceutical (small molecule) |
| format neat | format - | format neat | format neat |
| Quality Level 100 | Quality Level 200 | Quality Level - | Quality Level 300 |
| grade analytical standard | grade - | grade pharmaceutical primary standard | grade certified reference material, pharmaceutical secondary standard |
| assay ≥90.0% | assay ≥99.0% (HPLC) | assay - | assay - |
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Klasa składowania
11 - Combustible Solids
WGK
WGK 1
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
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What temperature should I store folinic acid calcium salt hydrate (F7878)? Is this reagent UV sensitive? Thanks.
1 answer-
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