A4730

Amthamine dihydrobromide

≥98% (HPLC), solid

• Synonim(y): 2-Amino-4-methyl-5-thiazoleethanamine dihydrobromide
• Wzór empiryczny (zapis Hilla): C₆H₁₁N₃S · 2HBr
• Numer CAS: 142457-00-9
• Masa cząsteczkowa: 319.06
• NACRES: NA.77
• PubChem Substance ID: 24890905
• UNSPSC Code: 12352200
• MDL number: MFCD00673891
• Assay: ≥98% (HPLC)
• Form: solid

Właściwości

• assay: ≥98% (HPLC)
• form: solid
• color: off-white
• solubility: H₂O: 27 mg/mL
• storage temp.: 2-8°C
• SMILES string: Br[H].Br[H].Cc1nc(N)sc1CCN
• InChI: 1S/C6H11N3S.2BrH/c1-4-5(2-3-7)10-6(8)9-4;;/h2-3,7H2,1H3,(H2,8,9);2*1H
• InChI key: XFXNNOPUDSFVJE-UHFFFAOYSA-N

Opis

Application

Amthamine dihydrobromide is a histamine H₂ receptor agonist. Amthamine dihydrobromide has been used to study the effect of mast cells on T regulatory cell function.

Biochem/physiol Actions

Amthamine dihydrobromide is a H₂ histamine receptor agonist. Amthamine dihydrobromide, similar to histamine, inhibits H₂ receptor-mediated eosinophil peroxidase (EPO) release with IC₅₀ = 0.4 μM; a weak antagonist at H₃ and shows no activity at H₁ receptors.

H₂ histamine receptor agonist.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 13 - Non Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable