This substance is synthetic organic. The product has been offered previously before 2023. See below for an example of the Certificate of Origin.
https://www.sigmaaldrich.com/coo/undefined/A5752/SHBL7005
A5752
Adrenochrome
>95% purity (HPLC), powder
Synonim(y):
3-Hydroxy-1-methyl-5,6-indolinedione
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25 MG
769,00 zł
250 MG
4130,00 zł
769,00 zł
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Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C9H9NO3
Numer CAS:
Masa cząsteczkowa:
179.17
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
200-192-8
MDL number:
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Pozwól nam pomócNazwa produktu
Adrenochrome, ≥95% (HPLC)
InChI key
RPHLQSHHTJORHI-UHFFFAOYSA-N
InChI
1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3
SMILES string
CN1CC(O)C2=CC(=O)C(=O)C=C12
assay
≥95% (HPLC)
form
powder
color
red to brown
εmax
3-4.5 at 485-490 nm in water, 9.0-10.5 at 299-304 nm in water
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
−20°C
Quality Level
Powiązane kategorie
1 of 4
Ta pozycja | 214515 | D7008 | N5625 |
|---|---|---|---|
| color red to brown | color - | color pink to very dark red | color - |
| application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing |
| form powder | form powder | form powder | form powder |
| storage temp. −20°C | storage temp. room temp | storage temp. −20°C | storage temp. −20°C |
| assay ≥95% (HPLC) | assay - | assay ≥95% | assay >99% (TLC) |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
Application
Adrenochrome has been used to study the effect of adrenochrome on coronary artery constriction in the rat heart.[1]
Biochem/physiol Actions
Adrenochrome is an oxidation product of adrenaline.[2] It has been implicated in cardiotoxicity.[3][4] It is a short-lived cytotoxic molecule and is part of the leukocyte response used to kill bacteria.[5] Adrenochrome is also suggested to exhibit psychotomimetic effects.[6] It is used to determine superoxide dismutase activity.[7]
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related product
Numer produktu
Opis
Cennik
Klasa składowania
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Adrenochrome-induced coronary artery constriction in the rat heart.
Karmazyn M, et al.
Journal of Pharmacology and Experimental Therapeutics, 219, 225-225 (1981)
Maria Luisa Genova et al.
Archives of biochemistry and biophysics, 447(2), 167-173 (2006-02-21)
Complex I in bovine heart submitochondrial particles catalyses the NADH-supported generation of superoxide anion; adrenaline is oxidised by superoxide to adrenochrome that, on its hand, is reduced by Complex I, thus establishing a redox cycle that amplifies the superoxide production.
Janna Shainsky et al.
Applied and environmental microbiology, 75(14), 4711-4719 (2009-05-26)
Enantiopure sulfoxides are prevalent in drugs and are useful chiral auxiliaries in organic synthesis. The biocatalytic enantioselective oxidation of prochiral sulfides is a direct and economical approach for the synthesis of optically pure sulfoxides. The selection of suitable biocatalysts requires
Viviana S Fluxá et al.
Nature protocols, 3(8), 1270-1277 (2008-08-21)
The adrenaline test for enzymes is a colorimetric enzyme assay based on the quantification of periodate-sensitive reaction products such as 1,2-diols and 1,2-aminoalcohols by back-titration of the oxidant with adrenaline to produce adrenochrome as an easily detectable red product. The
The oxidative metabolism of catecholamines in the brain: a review.
Smythies J and Galzigna L
Biochimica et Biophysica Acta, 1380, 159-159 (1998)
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Is this substance synthetic or naturally derived? Some download able Data on this product is dated 1/16/2023. Is this a relatively new substance?
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