While comparison studies between Silicone Antifoam and Antifoam Y-30 Emulsion in e. coli applications have not been conducted, it is likely that Antifoam Y-30 emulsion can be utilized similarly to the Silicone Antifoam. As noted in the technical bulletins, linked below, the former has a 30% active silicone content and the latter has 20% active silicone. As such, optimization of the current volume of antifoam may be necessary.
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/136/342/a5758pis.pdf
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/109/197/85390dat.pdf
General directions of use for Antifoam Y-30 emulsions are noted below:
Antifoam Y-30 Emulsion can be prediluted with
3-10 parts of cool water to aid in dispersion. Prediluted
suspensions should be used immediately. Antifoam
Y-30 Emulsion is typically effective at 1-100 ppm. The
flow properties of Antifoam Y-30 Emulsion are such that
it can be pumped on an as-needed basis to the fermentor
system with sufficient agitation to disperse the antifoam.