This product is constructed with a single deletion of Asp from the N-terminus to create a hypoallergenic construct. Structural equivalence to native albumin is confirmed by x-ray crystallography. The Asp deletion eliminates an important antigenic determinant by removing the principal copper and nickel binding site of albumin. The first three residues of human albumin are considered non-structural. Additionally, the product is blocked at Cys34 to improve stability, monomer content, and homogeneity.
Przejdź do
A7736
Albumin human
recombinant, expressed in Pichia pastoris, lyophilized powder, ≥90% (agarose gel electrophoresis)
Synonim(y):
Albagen™, rHSA
Zaloguj się, aby wyświetlić ceny organizacyjne i kontraktowe.
Wybierz wielkość
Zmień widok
| Rozmiar/SKU | Dostępność | Cena netto |
|---|---|---|
1 g | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 684,00 zł |
Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C2936H4624N786O889S41
Numer CAS:
Masa cząsteczkowa:
66471.53
UNSPSC Code:
12352202
NACRES:
NA.25
EC Number:
274-272-6
MDL number:
eCl@ss:
42010201
Biological source:
human
Assay:
≥90% (agarose gel electrophoresis)
Form:
lyophilized powder
Technique(s):
cell culture | mammalian: suitable
684,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Pomoc techniczna
Potrzebujesz pomocy? Nasz zespół doświadczonych naukowców chętnie Ci pomoże.
Pozwól nam pomócbiological source
human
Quality Segment
recombinant
expressed in Pichia pastoris
assay
≥90% (agarose gel electrophoresis)
form
lyophilized powder
mol wt
monomer ~67 kDa
technique(s)
cell culture | mammalian: suitable
UniProt accession no.
storage temp.
2-8°C
SMILES string
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
Gene Information
human ... ALB(213)
General description
Construct with a single deletion of Asp from the N-terminus to create a hypoallergenic construct. Structural equivalence to native albumin confirmed x-ray crystallography. The Asp deletion eliminates an important antigenic determinant by eliminating the principal copper and nickel binding site of albumin. The first three residues of human albumin are considered non-structural. Also blocked at Cys34 to improve stability, monomer content and homogeneity.
Application
This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.
Biochem/physiol Actions
Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.
Other Notes
View more information on human serum albumin.
Legal Information
Albagen is a trademark of Albumin Therapeutics, LLC.
Ta strona może zawierać tekst przetłumaczony maszynowo.
1 of 1
Ta pozycja | |||
|---|---|---|---|
| description recombinant, expressed in Pichia pastoris, lyophilized powder, ≥90% (agarose gel electrophoresis) | description recombinant, expressed in Saccharomyces cerevisiae, aqueous solution, 10% in aqueous buffer, ≥99% (agarose gel electrophoresis) | description United States Pharmacopeia (USP) Reference Standard | description lyophilized powder |
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) cell culture | mammalian: suitable |
| assay ≥90% (agarose gel electrophoresis) | assay ≥99% (agarose gel electrophoresis) | assay - | assay 90-100% protein basis (biuret) |
| biological source human | biological source human | biological source - | biological source human |
| Quality Level 300 | Quality Level 200 | Quality Level - | Quality Level 200 |
| form lyophilized powder | form aqueous solution | form liquid | form lyophilized powder |
| Gene Information human ... ALB(213) | Gene Information human ... ALB(213) | Gene Information - | Gene Information human ... ALB(213) |
Still not finding the right product?
Explore all of our products under Albumin human
Klasa składowania
10 - Combustible liquids
Co się dzieje?
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Wybierz jedną z najnowszych wersji:
Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
-
Hi there, I am looking at the product A7736 recombinant human albumin and I see it is "Albagen™ synonym" according to the description. I know that Albagen has a single deletion N-terminus. So it is not 100% HSA. what about A7736?
1 answer-
Helpful?
-