A9736

A-438079 hydrochloride hydrate

≥98% (HPLC), P2X7 purinoceptor antagonist, powder

• Synonim(y): 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methyl pyridine hydrochloride hydrate
• Wzór empiryczny (zapis Hilla): C₁₃H₉Cl₂N₅·HCl · xH₂O
• Numer CAS: 899431-18-6
• Masa cząsteczkowa: 342.61 (anhydrous basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 329771058
• NACRES: NA.77
• MDL number: MFCD17215929
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Właściwości

• Nazwa produktu: A-438079 hydrochloride hydrate, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• originator: Abbott
• storage temp.: 2-8°C
• SMILES string: O.Cl.Clc1cccc(c1Cl)-c2nnnn2Cc3cccnc3
• InChI: 1S/C13H9Cl2N5.ClH.H2O/c14-11-5-1-4-10(12(11)15)13-17-18-19-20(13)8-9-3-2-6-16-7-9;;/h1-7H,8H2;1H;1H2
• InChI key: ZHFJJBAKSROKNO-UHFFFAOYSA-N

Opis

Application

A-438079 hydrochloride hydrate has been used to determine its inhibitory effect on purinergic receptors. It has also been used to check its inhibitory effects on macrophages.

Biochem/physiol Actions

A-438079 hydrochloride hydrate is a selective P2X7 purinoceptor antagonist

A-438079 hydrochloride hydrate is a selective P2X7 purinoceptor antagonist in both human and rat with minimal activity at 75 different G-protein-coupled receptors, enzymes, transporters, and ion channels tested.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable