C0868

Chromeceptin

≥98% (HPLC), solid

• Synonim(y): 2-Amino-3-cyano-7-dimethylamino-4-(3-trifluoromethylphenyl)-4H-chromene, 94G6
• Wzór empiryczny (zapis Hilla): C₁₉H₁₆F₃N₃O
• Numer CAS: 331859-86-0
• Masa cząsteczkowa: 359.35
• NACRES: NA.77
• PubChem Substance ID: 24724431
• UNSPSC Code: 51111800
• MDL number: MFCD00815850
• Assay: ≥98% (HPLC)
• Form: solid

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• color: yellow to brown
• solubility: H₂O: <2 mg/mL, DMSO: >20 mg/mL
• storage temp.: −20°C
• SMILES string: CN(C)c1ccc2C(c3cccc(c3)C(F)(F)F)C(C#N)=C(N)Oc2c1
• InChI: 1S/C19H16F3N3O/c1-25(2)13-6-7-14-16(9-13)26-18(24)15(10-23)17(14)11-4-3-5-12(8-11)19(20,21)22/h3-9,17H,24H2,1-2H3
• InChI key: GVINXTXGDDSXFQ-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

Chromeceptin binds to multifunctional protein 2 (MFP-2); inhibits Insulin-like growth factor 2 (IGF2) signaling.

Chromeceptin inhibits Insulin-like growth factor 2 (IGF2) signaling by a process that begins with chromeceptin binding to multifunctional protein 2 (MFP-2). This interaction stimulates the expression of IGF binding protein 1 (IGFBP-1) and suppressor of cytokine signaling-3 (SOCS-3), both of which activate signal transducers and activators of transcription 6 (STAT6) to attenuate IGF signals.

Features and Benefits

This compound is featured on the InsR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable