C130

Chloro-APB hydrobromide

solid

• Synonim(y): (±)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, (±)-SKF-82958 hydrobromide, 6-Chloro-N-allyl-SKF-38393 hydrobromide
• Wzór empiryczny (zapis Hilla): C₁₉H₂₀ClNO₂ · HBr
• Numer CAS: 80751-65-1
• Masa cząsteczkowa: 410.73
• NACRES: NA.77
• PubChem Substance ID: 24277890
• UNSPSC Code: 12352200
• MDL number: MFCD00069235
• Form: solid

Właściwości

• form: solid
• Quality Segment: 100
• color: tan
• solubility: H₂O: 3.7 mg/mL, aqueous base: unstable, ethanol: soluble
• storage temp.: 2-8°C
• SMILES string: Br.Oc1cc2C(CN(CCc2c(Cl)c1O)CC=C)c3ccccc3
• InChI: 1S/C19H20ClNO2.BrH/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13;/h2-7,11,16,22-23H,1,8-10,12H2;1H
• InChI key: WLXGFAVTAAQOFH-UHFFFAOYSA-N
• Gene Information: human ... DRD1(1812)

Opis

Application

Chloro-APB hydrobromide has been used to pharmacologically stimulate D1 dopamine receptors and study its influence on locomotor response in fat mass and obesity-associated protein (FTO) deficient dopamine D1 receptor-expressing medium spiny neurons (D1 MSNs) of mice.

Biochem/physiol Actions

Chloro-APB hydrobromide, also known as SKF 82958, is a D1 dopamine receptor agonist. D1 receptor agonists prevent and reverse fentanyl-induced respiratory depression, without impairing opioid analgesia, in cats.

Disclaimer

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): Eyeshields, Gloves, type N95 (US)