The B9059 BACE-1 product included in the kit, serves as a positive control. The Technical Bulletin notes that the concentration of this item is approximate 3 units/microliter. This material has not been tested for purity. Therefore, a molar concentration cannot be provided.
Przejdź do
CS0010
β-Secretase (BACE1) Activity Detection Kit (Fluorescent)
1 kit sufficient for 250 reactions
Synonim(y):
BACE1 Activity Detection Kit (Fluorescent)
Zaloguj się, aby wyświetlić ceny organizacyjne i kontraktowe.
Wybierz wielkość
Zmień widok
| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 1 kit | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 5710,00 zł |
Informacje o tej pozycji
NACRES:
NA.84
UNSPSC Code:
12161503
5710,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Pomoc techniczna
Potrzebujesz pomocy? Nasz zespół doświadczonych naukowców chętnie Ci pomoże.
Pozwól nam pomócQuality Level
usage
kit sufficient for 250 reactions
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... BACE1(23621)
Application
The kit provides all the reagents required for an efficient detection of BACE1 activity. It contains an enzyme to be used for screening for potential BACE1 inhibitors. The assay is based on the fluorescence resonance energy transfer (FRET) method in which the fluorescence signal enhancement is observed after substrate cleavage by BACE1.
Biochem/physiol Actions
BACE1 is a transmembrane protease responsible for the β site cleavage of the amyloid precursor protein (APP) to produce amyloid β peptide (Aβ). The accumulation of Aβ in the brain is a primary cause for the progression of Alzheimer′s. BACE1 is a target for inhibitor drug discovery.
Ta strona może zawierać tekst przetłumaczony maszynowo.
1 of 1
Ta pozycja | |||
|---|---|---|---|
| storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. - |
| usage kit sufficient for 250 reactions | usage - | usage - | usage - |
| Gene Information human ... BACE1(23621) | Gene Information human ... BACE1(23621) | Gene Information human ... BACE1(23621) | Gene Information human ... BACE1(23621) |
| Quality Level 300 | Quality Level 200 | Quality Level - | Quality Level 100 |
| shipped in wet ice | shipped in wet ice | shipped in wet ice | shipped in wet ice |
Tylko elementy zestawu
Numer produktu
Opis
- Fluorescent Assay Buffer 50 mL
- Stop Solution 15 mL
- Substrate (MOCA-SEV-NL-DAEFR-DNP-RR) 500 μL
- Assay Standard 140 μL
- BACE1 (β−Secretase) 300 units 100 μL
Klasa składowania
10 - Combustible liquids
wgk
WGK 3
Wybierz jedną z najnowszych wersji:
Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Powiązane treści
Changxing Qi et al.
Fitoterapia, 130, 134-139 (2018-08-31)
Terrusnolides A-D (1-4), four butenolides were isolated from an endophytic Aspergillus from Tripterygium wilfordii. The structures of 1-4 were established by comprehensive spectroscopic analyses and electronic circular dichroism (ECD) calculation. It is interesting that 1 was a butenolide derived by
Vijay K Nuthakki et al.
Bioorganic chemistry, 90, 103062-103062 (2019-06-21)
Alkaloids have always been a great source of cholinesterase inhibitors. Numerous studies have shown that inhibiting acetylcholinesterase as well as butyrylcholinetserase is advantageous, and have better chances of success in preclinical/ clinical settings. With the objective to discover dual cholinesterase
Raúl Horacio Camarillo-López et al.
Molecules (Basel, Switzerland), 25(21) (2020-11-04)
Alzheimer's disease (AD) is a neurodegenerative disease with no cure nowadays; there is no treatment either to prevent or to stop its progression. In vitro studies suggested that tert-butyl-(4-hydroxy-3-((3-(2-methylpiperidin-yl)propyl)carbamoyl)phenyl) carbamate named the M4 compound can act as both β-secretase and
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| CS0010-1KT | 04061833553053 |
-
what is the concentration of BACE1 enzyme in micromolar?
1 answer-
Helpful?
-