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E1257

Epidermal Growth Factor from murine submaxillary gland

Name: Epidermal Growth Factor from murine submaxillary gland
Brand: SIGMA
Price: 1920 PLN

lyophilized powder, BioReagent, suitable for cell culture

Synonim(y):

EGF, Epidermal cell growth factor

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Rozmiar/SKU	Dostępność	Cena netto
0.1 mg	Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności	1920,00 zł

Informacje o tej pozycji

Numer CAS:

62229-50-9

UNSPSC Code:

12352202

EC Number:

263-468-7

NACRES:

NA.32

MDL number:

MFCD01634807

1920,00 zł

Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności

Pomoc techniczna

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Pozwól nam pomóc

Właściwości

biological source

mouse submaxillary glands

Quality Segment

200

product line

BioReagent

assay

≥98% (SDS-PAGE)

form

lyophilized powder

potency

0.02-2.0 ng/mL EC₅₀

packaging

pkg of 0.1 mg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

UniProt accession no.

P01132

storage temp.

2-8°C

Gene Information

mouse ... Egf(13645)

Opis

General description

Epidermal growth factor (EGF) is the member of EGF-like family of growth factors, that binds to EGF receptor. It is majorly expressed in kidney, parotid gland and salivary gland.

Application

Epidermal Growth Factor from murine submaxillary gland has been used

in studying its effects on the development of caustic esophageal stricture in rats
for preparation of MCF-10A cell line
for the culture of primary hair follicle stem cells from arbas cashmere goat (gHFSCs) and adhesion of hair follicles (HF)

Biochem/physiol Actions

Epidermal growth factor (EGF) blocks gastric acid and pepsin secretion and increases gastrointestinal cell proliferation. EGF stimulates proliferation and migration in bone marrow stromal cells (BMSC), that gives rise to osteoblasts, chondrocytes and adipocytes. It functions as a strong mitogenic factor for various cultured cells. Mutations in this gene is linked to hypomagnesemia. EGF plays a major role in the maintenance of hair and skin development.

Physical form

Lyophilized from 0.2 μm filtered solution in ammonium acetate buffer.

Preparation Note

Purified by gel filtration and ion-exchange chromatography.

Analysis Note

The biological activity is measured in a proliferation assay using BALB/MK cells.

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Ta pozycja	N0513	SRP3238	GF155
Sigma-Aldrich E1257 Epidermal Growth Factor from murine submaxillary gland	Sigma-Aldrich N0513 Nerve Growth Factor-7S from murine submaxillary gland	Sigma-Aldrich SRP3238 EGF from rat	Sigma-Aldrich GF155 Epidermal Growth Factor Protein, Recombinant mouse
description lyophilized powder, BioReagent, suitable for cell culture	description NGF-7S, lyophilized powder, suitable for cell culture	description recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture	description The Epidermal Growth Factor (EGF) is a polypeptide growth factor, which stimulates the proliferation of a wide range of epidermal & epithelial cells.
assay ≥98% (SDS-PAGE)	assay -	assay ≥98% (SDS-PAGE), ≥98% (HPLC)	assay >98% (SDS-PAGE)
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) -
biological source mouse submaxillary glands	biological source mouse	biological source rat	biological source -
Quality Level 200	Quality Level 200	Quality Level -	Quality Level 100
form lyophilized powder	form lyophilized powder	form lyophilized	form -
impurities endotoxin, tested	impurities ≤10	impurities <0.1 EU/μg endotoxin, tested	impurities <0.1 ng/μg Endotoxin (of EGF; 1EU/ug)

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Klasa składowania

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c