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F8758

Folic acid

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥97%

Synonim(y):

Pterylmonoglutamic acid, PteGlu, Pteroyl-L-glutamic acid, Vitamin M

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Do Państwa/SKUDostępnośćCena netto
5 g
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
260,00 zł
25 g
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
628,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C19H19N7O6
Numer CAS:
Masa cząsteczkowa:
441.40
NACRES:
NA.75
PubChem Substance ID:
eCl@ss:
34058014
UNSPSC Code:
12352205
EC Number:
200-419-0
MDL number:
Beilstein/REAXYS Number:
100781

260,00 zł


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biological source

synthetic

Quality Segment

product line

BioReagent

assay

≥97%

form

powder

mol wt

Mw 441.40 g/mol

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

color

dark yellow

solubility

1 M NaOH: soluble 50 mg/mL, clear to very slightly hazy, faintly yellow to dark yellow-orange

storage temp.

room temp

SMILES string

NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O

InChI

1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

InChI key

OVBPIULPVIDEAO-LBPRGKRZSA-N

General description

Folic acid (FA)/pterylmonoglutamic acid helps to block neural tube defects (NTDs).

Application

Folic acid has been used:
  • to study the role of vitamins and amino acids on hybridoma growth and monoclonal antibody production
  • in cells and treatments
  • in perforin gene targeting using the CRISPR/Cas gene editing approach

Biochem/physiol Actions

A nutritional delivery form of folate. Folic acid and its derivatives are essential mediators of one-carbon metabolism within cells.
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Ta pozycja
PHR10351286005F7876
Folic acid United States Pharmacopeia (USP) Reference Standard

USP

1286005

Folic acid

description

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥97%

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

United States Pharmacopeia (USP) Reference Standard

description

≥97%

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable

assay

≥97%

assay

-

assay

-

assay

≥97%

biological source

synthetic

biological source

-

biological source

-

biological source

synthetic (organic)

form

powder

form

-

form

-

form

powder

storage temp.

room temp

storage temp.

2-30°C

storage temp.

-

storage temp.

room temp

solubility

1 M NaOH: soluble 50 mg/mL, clear to very slightly hazy, faintly yellow to dark yellow-orange

solubility

-

solubility

-

solubility

-


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Klasa składowania

11 - Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)



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Lot/Batch Number

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Questions

1–5 of 5 Questions  
  1. Is it better to store folic acid (Product No. F8758) solution at RT or -20'C? Also, how long is it stable as a solution for at recommended temperature?

    1 answer
    1. Solution stability has not been determined for this product, however commercial and pharmaceutical preparations are cited as being stable at room temperature for up to 18 months, protected from light. Folic acid is also a component of most of the classical DMEM media formulations, for example D5546. These products are also assigned a shelf life of 18 months, but are stored at 2 - 8 deg. C. Storing at -20 deg. C may or may not extend the shelf life. There is a possibility that the freeze/thaw process may result in precipitation and may be detrimental.

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  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  3. What is the solubility of folic acid (Product No. F8758)?

    1 answer
    1. Product No. F8758 is soluble in 1 M NaOH (50 mg/mL). The free acid is only slightly soluble in water (0.01 mg/mL at 0 °C), and is insoluble in aqueous solutions below pH 5. It is soluble in sodium bicarbonate or sodium hydroxide solutions.

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  4. Is Product No. F8758, Folic Acid, tested for endotoxins?

    1 answer
    1. No, Product No. F8758 has not been tested for endotoxins. This product has, however, been tested for use in mammalian cell culture and insect cell culture.

      Helpful?

  5. What is the stability of folic acid (Product No. F8758) once in solution?

    1 answer
    1. This product is photolabile and is inactivated by UV light. Alkaline solutions are reasonably stable in the dark, but heating will destroy both alkaline and acidic solutions.

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