F9427

Fexofenadine hydrochloride

>98% (HPLC), H1 histamine receptor antagonist, powder

• Synonim(y): Fexofenidine hydrochloride, MDL 16455 hydrochloride, Terfenidine carboxylate hydrochloride
• Wzór empiryczny (zapis Hilla): C₃₂H₃₉NO₄ · HCl
• Numer CAS: 153439-40-8
• Masa cząsteczkowa: 538.12
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278447
• NACRES: NA.77
• MDL number: MFCD00865710
• Assay: >98% (HPLC)
• Form: powder
• Storage condition: desiccated

Właściwości

• Nazwa produktu: Fexofenadine hydrochloride, >98% (HPLC)
• Quality Segment: 100
• assay: >98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: soluble ≥5 mg/mL
• originator: Sanofi Aventis
• storage temp.: −20°C
• SMILES string: Cl[H].CC(C)(C(O)=O)c1ccc(cc1)C(O)CCCN2CCC(CC2)C(O)(c3ccccc3)c4ccccc4
• InChI: 1S/C32H39NO4.ClH/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27;/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36);1H
• InChI key: RRJFVPUCXDGFJB-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Opis

Application

Fexofenadine hydrochloride has been used as a non-cationic ampliphilic antihistamines in NCI-H661 cells and as a histamine H1 receptor antagonist in mice

Biochem/physiol Actions

Fexofenadine is used in treating allergic rhinitis and chronic idiopathic urticaria. It may give relief in bothersome symptom and is a second-generation antihistamines. Fexofenadine provides better relief compared to other antihistamines for nasal congestion. It is the active metabolite of terfenadine and bring down allergen-induced symptoms.

Fexofenadine is a non-sedating H1 histamine receptor antagonist.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): Eyeshields, Gloves, type N95 (US)