H4131

Hemoglobin porcine

lyophilized powder

• Synonim(y): Hb
• Numer CAS: 9008-02-0
• UNSPSC Code: 12352202
• eCl@ss: 42030116
• NACRES: NA.61
• MDL number: MFCD00131282
• Form: lyophilized powder
• Biological source: Porcine

Właściwości

• biological source: Porcine
• Quality Segment: 200
• form: lyophilized powder
• solubility: H₂O: soluble 10 mg/mL
• UniProt accession no.: P02067, P02101
• storage temp.: 2-8°C
• Gene Information: pig ... HBB(407066), HBE1(407067)

Opis

General description

Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.

Application

Hemoglobin from porcine was used to test the role of the L-arginine/nitric oxide pathway in relaxation of isolated human penile cavernous tissue and circumflex veins. It was also used to study the role of nitric oxide in neurogenic vasodilation of porcine cerebral artery.

Biochem/physiol Actions

Oxygen transporter, NO scavenger

The Fe²⁺/Fe³⁺ balance is a physiological indicator of blood oxygenation. Deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

Disclaimer

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• WGK: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): Eyeshields, Gloves, type N95 (US)