I0531

Interleukin-18 from rat

>97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

• UNSPSC Code: 12352202
• NACRES: NA.32
• MDL number: MFCD01867247

Właściwości

• biological source: rat
• Quality Segment: 200
• recombinant: expressed in E. coli
• assay: >97% (SDS-PAGE)
• form: lyophilized powder
• potency: 10-60 ng/mL ED₅₀
• mol wt: predicted mol wt ~18.4 kDa
• packaging: pkg of 25 μg
• impurities: endotoxin, tested
• UniProt accession no.: Q16552
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: rat ... Il18(29197)

Opis

Biochem/physiol Actions

Interleukin 18, also known as interferon-γ-inducing factor (IGIF) and IL-1γ, is a proinflammatory cytokine. It is an inducer of IFN-γ and Th1 (T cell helper type 1) responses (cell differentiation, cell-mediated cytotoxicity and inflammation). IL-18 induces the migration of microvascular endothelial cells.

Physical form

Lyophilized from 20 mM Tris , 500 mM NaCl, 0.5 mM EDTA, 1 mM TCEP, 0.05% (w/v) PEG8000 pH 8.0 with 5% Trehalose,and 50 μg BSA per μg IL-18

Analysis Note

The biological activity is measured by its ability to induce mouse IFN-γ production by activated mouse T cells.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• WGK: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable