I9404

Interleukin-10/Fc Chimera (non-lytic) human

>98% (SDS-PAGE), recombinant, expressed in NS.1 cells, buffered aqueous solution

• Synonim(y): IL-10:Fc (non-lytic) human
• UNSPSC Code: 51111800
• NACRES: NA.32
• MDL number: MFCD03457245
• Form: buffered aqueous solution
• Assay: >98% (SDS-PAGE)
• Biological source: human
• Recombinant: expressed in NS.1 cells
• Mol wt: 98 kDa

Właściwości

• biological source: human
• Quality Segment: 200
• recombinant: expressed in NS.1 cells
• assay: >98% (SDS-PAGE)
• form: buffered aqueous solution
• mol wt: 98 kDa
• packaging: pkg of 10 μg
• impurities: endotoxin, tested
• UniProt accession no.: P22301
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... IL10(3586)

Opis

General description

The gene IL-10 (interleukin-10) is mapped to human chromosome 1q31-32. It is secreted by monocytes and lymphocytes.

Biochem/physiol Actions

IL-10 (interleukin-10) is an anti-inflammatory cytokine. High levels of IL-10 are present in late syphilis. It suppresses Th1 (T helper) cytokines. IL-10 also controls the differentiation and proliferation of T cells, B cells, natural killer cells, antigen-presenting cells and mast cells.

Possesses the biological function of the IL-10 moiety and a prolonged circulating half-life determined by the Fc domain.

Physical form

Solution in 0.2 μm filtered phosphate buffered saline, pH 7.4.

Other Notes

Dimeric fusion protein consisting of human IL-10 fused to mutant human IgG1 Fc.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 10 - Combustible liquids
• Co się dzieje?: WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable