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M3064

Myostatin human

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonim(y):

GDF-8, Growth Differentiation Factor - 8

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Informacje o tej pozycji

UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:
Biological source:
human
Recombinant:
expressed in E. coli
Assay:
≥95% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
16 kDa (including a 31 amino-acid spacer and 6-His tag)


biological source

human

Quality Segment

recombinant

expressed in E. coli

assay

≥95% (SDS-PAGE)

form

lyophilized powder

mol wt

16 kDa (including a 31 amino-acid spacer and 6-His tag)

packaging

pkg of 0.1 mg

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

storage temp.

−20°C

Application

Use recombinant myostatin to study its mechanisms of action in vitro.

Biochem/physiol Actions

Myostatin is a 25 KDa, homodimer, that acts on muscle to induce SMAD family transcription factors such as SMAD2 and SMAD3. It inhibits the differentiation of myoblasts into mature muscle fibers. Positive control for myostatin in Western blots and ELISA.
Positive control for myostatin in Western blots and ELISA.
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Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Lot/Batch Number

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Questions

  1. Is this the active/mature myostatin protein or does is it the proprotein before being activated?

    1 answer
    1. This product is not an active/mature myostatin protein. The sequence used for this myostatin protein is residues 267 - 375. The recombinant protein also includes an N-terminal His tag followed by a spacer before the myostatin sequence.

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