M6885

1-Methyluric acid

• Synonim(y): 1-Methyl-2,6,8-trihydroxypurine, 1-U, 1MUA
• Wzór empiryczny (zapis Hilla): C₆H₆N₄O₃
• Numer CAS: 708-79-2
• Masa cząsteczkowa: 182.14
• UNSPSC Code: 41106305
• NACRES: NA.51
• PubChem Substance ID: 24897125
• EC Number: 211-905-7
• Beilstein/REAXYS Number: 195190
• MDL number: MFCD00042987

Właściwości

• assay: ≥98% (HPLC)
• form: powder
• solubility: 1 M NaOH: 20 mg/mL, clear to slightly hazy
• SMILES string: CN1C(=O)NC2=C(NC(=O)N2)C1=O
• InChI: 1S/C6H6N4O3/c1-10-4(11)2-3(9-6(10)13)8-5(12)7-2/h1H3,(H,9,13)(H2,7,8,12)
• InChI key: QFDRTQONISXGJA-UHFFFAOYSA-N

Opis

Application

1-Methyluric acid has been used:

• for the determination of uric acid in stool samples by liquid chromatography and tandem mass spectrometry
• in turbidimetric assay of synthetic urine samples
• as a substrate for CYP1A2(cytochrome P450 family 1 subfamily A member 2) assay

Biochem/physiol Actions

1-Methyluric acid (1-U) is a major metabolite of caffeine and theophylline with antioxidant activity that protects molecules such as low density lipoproteins (LDL) from oxidative modifications. 1-Methyluric acid may be used in studies aimed at differentiating the activities of caffeine and theophylline metabolites.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): Eyeshields, Gloves, type N95 (US)