N151

Nisoxetine hydrochloride

≥98% (HPLC), Norepinephrine reuptake inhibitor, solid

• Synonim(y): (±)-γ-(2-Methoxyphenoxy)-N-methyl-benzenepropanamine hydrochloride, LY-94,939
• Wzór empiryczny (zapis Hilla): C₁₇H₂₁NO₂ · HCl
• Numer CAS: 57754-86-6
• Masa cząsteczkowa: 307.82
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277788
• NACRES: NA.77
• MDL number: MFCD00153850
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: desiccated

Właściwości

• Nazwa produktu: Nisoxetine hydrochloride, solid, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 20 mg/mL, ethanol: 50 mg/mL
• SMILES string: Cl[H].CNCCC(Oc1ccccc1OC)c2ccccc2
• InChI: 1S/C17H21NO2.ClH/c1-18-13-12-15(14-8-4-3-5-9-14)20-17-11-7-6-10-16(17)19-2;/h3-11,15,18H,12-13H2,1-2H3;1H
• InChI key: LCEURBZEQJZUPV-UHFFFAOYSA-N

Opis

Application

Nisoxetine has been used as a norepinephrine transport (NET) blocker in autoradiography studies. It has also been used as a NET blocker to study its effects on perivascular adipose tissue.

Biochem/physiol Actions

Nisoxetine is a selective and potent noradrenaline reuptake inhibitor. It has a high affinity towards the noradrenaline transporter. Nisoxetine possesses antidepressant activity.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)