The water content can be found on the lot-dependent Certificate of Analysis.
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P0037
PP242 hydrate
≥98% (HPLC), powder
Synonim(y):
2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol
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| Rozmiar/SKU | Dostępność | Cena netto |
|---|---|---|
5 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 1080,00 zł 918,00 zł |
Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C16H16N6O · xH2O
Numer CAS:
Masa cząsteczkowa:
308.34 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
918,00 zł
Cena katalogowa1080,00 złZaoszczędź 15%Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Pomoc techniczna
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Pozwól nam pomócQuality Segment
assay
≥98% (HPLC)
form
powder
color
off-white
solubility
DMSO: >10 mg/mL
storage temp.
2-8°C
SMILES string
O.CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c4c(N)ncnc14
InChI
1S/C16H16N6O.H2O/c1-8(2)22-16-13(15(17)18-7-19-16)14(21-22)12-6-9-5-10(23)3-4-11(9)20-12;/h3-8,20,23H,1-2H3,(H2,17,18,19);1H2
InChI key
FMDOLJSFPXFBIL-UHFFFAOYSA-N
Application
PP242 hydrate has been used:
- as a mammalian target of rapamycin (mTOR) inhibitor to study its effects on rat fibroblast mTOR complex 1 and 2 (mTORC1 & 2) signaling
- as an mTOR inhibitor to treat mouse embryonic fibroblasts (MEF) and cumulus cells (CCs) to study its effects on reactivation of embryonic nucleoli and ribosome biogenesis
- as a target of rapamycin (TOR) kinase inhibitor for the treatment of Arabidopsis to study its effects against Fusarium graminearum infection
Biochem/physiol Actions
PP242 is a potent and selective mTOR inhibitor.
PP242 is a potent and selective mTOR inhibitor. PP242 is a first selective inhibitor that targets ATP domain of mTOR.
Features and Benefits
This compound is featured on the PKB/Akt page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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Ta pozycja | |||
|---|---|---|---|
| description ≥98% (HPLC), powder | description The mTOR Inhibitor III, PP242 controls the biological activity of mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. | description ≥95% (HPLC) | description ≥98% (HPLC) |
| assay ≥98% (HPLC) | assay ≥97% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) |
| form powder | form solid | form powder | form powder |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: >10 mg/mL | solubility DMSO: 100 mg/mL | solubility DMSO: 2 mg/mL, clear (warmed) | solubility DMSO: ≥14 mg/mL |
| color off-white | color off-white | color white to beige | color white to tan |
Klasa składowania
11 - Combustible Solids
Co się dzieje?
WGK 2
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
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I would like to get information about the water content of the compound. It is written as X in the compound formula. How many water molecules are found in the PP242 hydrate molecule?
1 answer-
Helpful?
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What is the degree of hydration for this product?
1 answer-
The specification for the degree of hydration for this product is an elemental analysis value of H2O (moles) ranging from 0.0 to 3.0. The actual value can be found in the batch-specific Certificate of Analysis.
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