P1530
Synonim(y):
Poly (I:C), Poly(I) • Poly(C)
| Rozmiar/SKU | Dostępność | Cena netto |
|---|
(Free nucleotides NMT 1% (TLC))
lyophilized powder
desiccated
H2O: 10 mg/mL
−20°C
[Na].[P](=O)(OC[C@H]3O[C@H]([C@@H]([C@@H]3O)O)[n]4c5ncnc(c5nc4)O)(O)O.[P](=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)N2C=CC(=NC2=O)N)(O)O
1S/C10H13N4O8P.C9H14N3O8P.Na/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);/t
GETQKWBYQAUFQM-VRQAYDGLSA-N
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Ta pozycja | |||
|---|---|---|---|
| description 10% Poly (I:C) with buffer salts, TLR ligand tested | description γ-irradiated, 10% Poly (I:C) with buffer salts, TLR ligand tested | description Known to induce interferon production. Hypochromicity: ≥40% at 248 nm. Extinction coefficient = 5000 M-1cm-1 at 260 nm, pH 7.0. | description 10% Poly (I:C) with buffer salts, TLR ligand tested |
| Quality Level 300 | Quality Level 300 | Quality Level 100 | Quality Level 300 |
| form lyophilized powder | form lyophilized powder | form powder | form lyophilized powder |
| assay (Free nucleotides NMT 1% (TLC)) | assay (Free nucleotides NMT 1% (TLC)) | assay ≥99% (TLC) | assay (Free nucleotides NMT 1% (TLC)) |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| solubility H2O: 10 mg/mL | solubility H2O: 10 mg/mL | solubility water: soluble, aqueous buffer: 10 mg/mL | solubility - |
| storage condition desiccated | storage condition desiccated | storage condition OK to freeze | storage condition desiccated |
Explore all of our products under Polyinosinic–polycytidylic acid sodium salt
11 - Combustible Solids
WGK 3
Not applicable
Not applicable
Eyeshields, Gloves, type N95 (US)
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Filter-sterilization is not recommended for Poly (I:C) solutions. Should a sterile Poly (I:C) solution be required, see product II3036, a sterile 10% solution. Please see the following link to review additional information available in the product datasheet:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/112/503/p1530pis-ms.pdf
Please see the link below to review the γ-irradiated 10% Poly (I:C) solution:
https://www.sigmaaldrich.com/product/sigma/i3036
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No specific timing is recommended for heating and cooling. A gentle warming to 50 °C for a few minutes, followed by cooling to room temperature or as required in the experiment, is suggested.
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Product P1530 is not tissue culture sterile
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What is the molecular weight of Polyinosinic-Polycytidylic acid Sodium Salt (P1530)?
The Polyinosinic-Polycytidylic acid Sodium Salt (P1530) is a double-stranded homopolymer with variable molecular weights. The variable range has been observed at 400-1250 base pairs; however, this may vary from lot to lot.
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The product is a double-stranded homopolymer without a specified length. Historical data have shown a broad lot-to-lot variability with an approximate range of 200 - >1000 bp length.
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The product is double-stranded homopolymer without specified length,. Historical data have shown broad lot to lot variability with an approximately range of 200 - >1000 bp in length.
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The minimum purity specification for this item is 99%. However, this product it is not suitable for human use or GMP applications. Unless otherwise stated this product is intended for research use only and is not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Please see the link to below to review addtional information regarding our various quality levels:
https://www.sigmaaldrich.com/US/en/life-science/quality-and-regulatory-management/m-clarity-program
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