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P4247

Anti-Potassium Channel Kv1.3 (extracellular)−FITC antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonim(y):

Anti-Kcna3, Anti-Voltage-gated Potassium Channel KV1.3

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Rozmiar/SKUDostępnośćCena netto
50 μL
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3700,00 zł

Informacje o tej pozycji

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
FITC conjugate
Clone:
polyclonal
Application:
FACS, WB
Citations:
4

3700,00 zł


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biological source

rabbit

Quality Segment

conjugate

FITC conjugate

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat, human, mouse

technique(s)

flow cytometry: 0.5-5 μg/test using Jurkat T-cells, western blot: 1:200-1:500 using rat brain membranes

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KCNA3(3738)
mouse ... Kcna3(16491)
rat ... Kcna3(29731)

General description

The (K+) channel family has been sub-grouped in to 2 TM, 4 TM and 6 TM (K+) channels based on the number of transmembrane domains. The voltage-gated Potassium or (Kv) channels belong to the 6 TM (K+) channel family and are expressed mainly in hematopoietic cells such as T and B lymphocytes, macrophages and natural killer cells. (Kv)1.3 facilitates cell proliferation and can also regulate the immune system. Genetic alterations in (Kv) 1.3 lead to epilepsy, episodic ataxia/myokymia, and episodic cardiac arrhythmia (the long QT syndrome). Anti-potassium channel (Kv) 1.3 (extracellular)−FITC antibody can be used for western blotting of rat brain membranes. Rabbit anti- potassium channel (Kv) 1.3 (extracellular) antibodies reacts specifically with rat and human (Kv) 1.3.

Immunogen

synthetic peptide corresponding to residues 211-224 of human KV1.3. Rat and mouse are 12/14 residues identical.

Application

Anti-potassium channel (Kv) 1.3 (extracellular)−FITC antibody can be used in immunoblotting and flow cytometry.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, 1% bovine serum albumin, 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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description

affinity isolated antibody, lyophilized powder

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Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

description

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

affinity isolated antibody

antibody form

affinity purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

conjugate

FITC conjugate

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

shipped in

dry ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

species reactivity

rat, human, mouse

species reactivity

rat, mouse, human

species reactivity

human

species reactivity

human


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Klasa składowania

13 - Non Combustible Solids

Co się dzieje?

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable



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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

  1. Is there an isotype control for this Ab

    1 answer
    1. P4247 Sigma-Aldrich Anti-Potassium Channel Kv1.3 (extracellular)−FITC antibody produced in rabbit is a rabbit polyclonal antibody, so it is a rabbit IgG-type antibody. Since there are no isotypes/subtypes for rabbit polyclonal IgG, the most suitable negative control would be a normal (i.e., non-immune) rabbit IgG that is conjugated to FITC. Unfortunately at this time, we do not offer an antibody such as this; however, we offer normal rabbit IgG that is either unconjugated (which could be conjugated with FITC at the end-user's facility), or conjugated to other fluorophores, e.g., 16-237 Sigma-Aldrich Normal Rabbit IgG, Alexa Fluor® 488 conjugate.

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