P7036

Parathyroid hormone human

≥92% (HPLC), powder

• Synonim(y): PTH, Parathormone
• Wzór empiryczny (zapis Hilla): C₄₀₈H₆₇₄N₁₂₆O₁₂₆S₂
• Numer CAS: 68893-82-3
• Masa cząsteczkowa: 9424.62
• UNSPSC Code: 51111800
• NACRES: NA.32
• MDL number: MFCD00081830
• Biological source: synthetic (organic)
• Form: powder
• Assay: ≥92% (HPLC)

Właściwości

• biological source: synthetic (organic)
• Quality Segment: 200
• sterility: non-sterile
• assay: ≥92% (HPLC)
• form: powder
• composition: Peptide content, ≥70%
• solubility: water: 1 mg/mL, clear, colorless
• UniProt accession no.: P01270
• shipped in: ambient
• storage temp.: −20°C
• Gene Information: human ... PTH(5741)

Opis

General description

Parathyroid hormone (PTH) is a circulating hormone secreted from the parathyroid gland. This hormone is synthesized as a pre-pro hormone. PTH is composed of binding regions that have a high affinity to a receptor and functional domains that interact with the receptors to initiate an intracellular signaling cascade.

Application

Parathyroid hormone human has been used to incubate mature human adipocytes.

Biochem/physiol Actions

Parathyroid hormone (PTH) exerts its effects on bone and kidney cells. This hormone plays a role in calcium homeostasis. PTH is secreted from the chief cells of the parathyroid gland in response to low extracellular calcium levels or higher levels of extracellular phosphate. PTH deficiency or excess PTH are associated with hypoparathyroidism and hyperparathyroidism, respectively.

Other Notes

Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-Gly-Ala-Pro-Leu-Ala-Pro-Arg-Asp-Ala-Gly-Ser-Gln-Arg-Pro-Arg-Lys-Lys-Glu-Asp-Asn-Val-Leu-Val-Glu-Ser-His-Glu-Lys-Ser-Leu-Gly-Glu-Ala-Asp-Lys-Ala-Asp-Val-Asn-Val-Leu-Thr-Lys-Ala-Lys-Ser-Gln

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable