PRS2337

Anti-IKAP antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonim(y): Anti-IKBKAP, Anti-IKK complex-associated protein, Anti-Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD04118553
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ELISA (i), ICC, IF, WB
• Citations: 2

Właściwości

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: predicted mol wt 134-147 kDa
• species reactivity: mouse, human
• technique(s): immunocytochemistry: suitable, immunofluorescence: suitable, indirect ELISA: suitable, western blot: suitable
• UniProt accession no.: O95163
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... IKBKAP(8518)

Opis

General description

IKAP (IKK-complex-associated protein) is considered as a subunit of the RNA Pol II elongator complex. It is also known as IKBKAP (Ikappakinase complex-associated protein or human elongator factor 1) and ELP1 (elongator protein-1). It has 37 exons and codes for 1332 amino acid IKAP protein, that is of ~150KD. It is present in most of the tissues. It is mapped to chromosome 9q31.

Immunogen

a 16 amino acid peptide from near the carboxy-terminus of human IKAP.

Biochem/physiol Actions

Mutations in IKAP cause familial dysautonomia. It helps to conserve the proliferation of neural precursor and blocks its unexpected differentiation into neurons. It plays an important role in cell motility and migration.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Other Notes

The action of this antibody can be blocked using blocking peptide SBP2337.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Klasa składowania: 10 - Combustible liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable