SAB6012074

Anti Frizzled class receptor 8 Antibody, clone 23GB5470, Rabbit Monoclonal

clone 23GB5470, recombinant rabbit monoclonal, expressed in HEK293 cells

• Synonim(y): FZ-8, HFz8
• Kod UNSPSC: 12352203

Właściwości

• pochodzenie biologiczne: rabbit (Monoclonal)
• Poziom jakości: 100
• rekombinowane: expressed in HEK 293 cells
• białko sprzężone: unconjugated
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: 23GB5470, recombinant monoclonal
• Formularz: buffered aqueous glycerol solution
• masa cząsteczkowa: 73 kDa
• reaktywność gatunkowa: human
• opakowanie: vial of 1.5 mL
• rozszerzona walidacja: recombinant expression; Learn more about Antibody Enhanced Validation
• sustainability: Greener Alternative Product
• stężenie: 1 mg/ml
• metody: flow cytometry: 1:2000; western blot: 1:1,000-1:5,000
• izotyp: IgG
• Ensembl | numer dostępu dla gatunku człowiek: ENSG00000177283
• numer dostępu NCBI: NP_114072.1
• numer dostępu UniProt: Q9H461
• kategoria ekologicznej alternatywy: DfS-Developed
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... FZD8(8325)

Opis

Opis ogólny

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]

We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 640-694 of human Frizzled 8 [NP_114072.1].

Postać fizyczna

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Inne uwagi

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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