SAB6012087

Anti Dual specificity phosphatase 1 Antibody, clone 23GB5760, Rabbit Monoclonal

clone 23GB5760, recombinant rabbit monoclonal, expressed in HEK293 cells

• Synonim(y): HVH1, MKP-1, PTPN10
• Kod UNSPSC: 12352203

Właściwości

• pochodzenie biologiczne: rabbit (Monoclonal)
• Poziom jakości: 100
• rekombinowane: expressed in HEK 293 cells
• białko sprzężone: unconjugated
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: 23GB5760, recombinant monoclonal
• Formularz: buffered aqueous glycerol solution
• masa cząsteczkowa: 39 kDa
• reaktywność gatunkowa: human, rat
• opakowanie: vial of 1.5 mL
• rozszerzona walidacja: recombinant expression; Learn more about Antibody Enhanced Validation
• sustainability: Greener Alternative Product
• stężenie: 1.5 mg/ml
• metody: flow cytometry: 1:2000; western blot: 1:1,000-1:5,000
• izotyp: IgG
• Ensembl | numer dostępu dla gatunku człowiek: ENSG00000120129
• numer dostępu NCBI: NP_004408.1
• numer dostępu UniProt: P28562
• kategoria ekologicznej alternatywy: DfS-Developed
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... DUSP1(1843)

Opis

Opis ogólny

The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. [provided by RefSeq, Aug 2017]

We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 102-150 of human DUSP1 [NP_004408.1].

Postać fizyczna

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Inne uwagi

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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