SML0041

Batimastat

≥98% (HPLC), powder, matrix metalloproteinase inhibitor

• Synonim(y): BB-94; (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide
• Wzór empiryczny (zapis Hilla): C₂₃H₃₁N₃O₄S₂
• Numer CAS: 130370-60-4
• Masa cząsteczkowa: 477.64
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825111
• NACRES: NA.77
• MDL number: MFCD00866533
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Nazwa produktu: Batimastat, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: DMSO: ≥15 mg/mL
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc2cccs2)C(=O)NO
• InChI: 1S/C23H31N3O4S2/c1-15(2)12-17(18(22(28)26-30)14-32-20-10-7-11-31-20)21(27)25-19(23(29)24-3)13-16-8-5-4-6-9-16/h4-11,15,17-19,30H,12-14H2,1-3H3,(H,24,29)(H,25,27)(H,26,28)/t17-,18+,19+/m1/s1
• InChI key: XFILPEOLDIKJHX-QYZOEREBSA-N

Opis

Application

Batimastat has been used to inhibit matrix metalloproteinases (MMPs) activity in various studies.

Biochem/physiol Actions

Batimastat is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor.

Batimastat is hydroxamate-type inhibitor of matrix metalloproteinases (MMP). It inhibits the growth and spread of lung tumors, breast cancer regrowth and human colon tumor growth and spread in mouse models. Batimastat reduces MMP-mediated vascular dysfunction and vessel wall damage and enhances the sealing ability and bond strength of dental adhesives.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable