SML1097

BC8-15

≥98% (HPLC)

• Synonim(y): 3-[(3-Ethyl-1,2,4-triazolo[4,3-c]quinazolin-5-yl)amino]-benzoic acid
• Wzór empiryczny (zapis Hilla): C₁₈H₁₅N₅O₂
• Numer CAS: 950385-77-0
• Masa cząsteczkowa: 333.34
• UNSPSC Code: 41106305
• PubChem Substance ID: 329825474
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CCC1=NN=C2N1C(NC3=CC=CC(C(O)=O)=C3)=NC4=CC=CC=C42
• InChI: 1S/C18H15N5O2/c1-2-15-21-22-16-13-8-3-4-9-14(13)20-18(23(15)16)19-12-7-5-6-11(10-12)17(24)25/h3-10H,2H2,1H3,(H,19,20)(H,24,25)
• InChI key: INDKHRIZOIEPIG-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

BC8-15 is a potent PDE4/8 inhibitor that elevates steroidogenesis in mouse Leydig cells.

BC8-15 is a potent PDE4/8 inhibitor.

BC8-15 has the ability to block PDE8A (phosphodiesterase 8A) and PDE4A (phosphodiesterase 4A) with IC50 values of 280 and 220 nM. It helps to increase the synthesis of the steroid from both primary Leydig cells and MA-10 cells.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable