SML1360

Cariporide

≥98% (HPLC), selective inhibitor of the Na+/H+ exchanger subtype 1, powder

• Synonim(y): HOE-642, N-(Aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)-benzamide, N-(Diaminomethylene)-4-isopropyl-3-(methylsulfonyl)benzamide
• Wzór empiryczny (zapis Hilla): C₁₂H₁₇N₃O₃S
• Numer CAS: 159138-80-4
• Masa cząsteczkowa: 283.35
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825815
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Nazwa produktu: Cariporide, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: NC(NC(C1=CC(S(C)(=O)=O)=C(C(C)C)C=C1)=O)=N
• InChI: 1S/C12H17N3O3S/c1-7(2)9-5-4-8(11(16)15-12(13)14)6-10(9)19(3,17)18/h4-7H,1-3H3,(H4,13,14,15,16)
• InChI key: IWXNYAIICFKCTM-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

Cariporide is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1), also known as the Na+/H+ antiporter. Cariporide has shown cardioprotective and antiarrhythmic effects, and has recently been investigated for anticancer activity.

Cariporide is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1).

Cariporide, a sodium-hydrogen exchange inhibitor can decrease the liberation of myoglobin at the time of ischemia/reperfusion and reduces the liberation of NE (norepinephrine) during ischemia.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• WGK: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable