SML1854

Banoxantrone dihydrochloride

≥98% (HPLC)

• Synonim(y): 1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione, AQ4N dihydrochloride
• Wzór empiryczny (zapis Hilla): C₂₂H₂₈N₄O₆ · 2HCl
• Numer CAS: 252979-56-9
• Masa cząsteczkowa: 517.40
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD19690955
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: blue
• solubility: H₂O: 3 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: O=C1C2=C(C(NCC[N+](C)([O-])C)=CC=C2NCC[N+]([O-])(C)C)C(C3=C(O)C=CC(O)=C31)=O.[H]Cl.[H]Cl
• InChI: 1S/C22H28N4O6.2ClH/c1-25(2,31)11-9-23-13-5-6-14(24-10-12-26(3,4)32)18-17(13)21(29)19-15(27)7-8-16(28)20(19)22(18)30;;/h5-8,23-24,27-28H,9-12H2,1-4H3;2*1H
• InChI key: SBWCPHUXRZRTDP-UHFFFAOYSA-N

Opis

Application

Banoxantrone dihydrochloride has been used as an organic ligand during a self-assembled metal-organic coordinated nanoparticle (Cu–OCNP/Lap) synthesis. It has also been used for the preparation of supramolecularly functionalized graphene oxide for hypoxia-activated chemotherapy of cancer.

Biochem/physiol Actions

Banoxantrone (AQ4N) is a hypoxia-activated prodrug of topoisomerase II inhibitor AQ4 (Bioreductive AQ4 precursor).

Hypoxia-activated prodrug of topoisomerase II inhibitor AQ4

Banoxantrone dihydrochloride enhances the anti-tumor effect caused by radiation.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• WGK: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable