SML2187

RL5a

≥98% (HPLC)

• Synonim(y): N2-[2-(2-Furanyl)-4-quinolinyl]-N1,N1-dimethyl-1,2-ethanediamine
• Wzór empiryczny (zapis Hilla): C₁₇H₁₉N₃O
• Numer CAS: 133671-66-6
• Masa cząsteczkowa: 281.35
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD00929354
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• assay: ≥98% (HPLC)
• form: powder
• color: white to very dark brown
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: N(CCNc1c2c(nc(c1)c3[o]ccc3)cccc2)(C)C
• InChI: 1S/C17H19N3O/c1-20(2)10-9-18-15-12-16(17-8-5-11-21-17)19-14-7-4-3-6-13(14)15/h3-8,11-12H,9-10H2,1-2H3,(H,18,19)
• InChI key: CRGKLHXVNVZAPA-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

RL5a is a potent inhibitor of the replication licensing system in human cells. RL5a blocks the binding of the origin recognition complex (ORC) to origin DNA, which is required interaction for licensing. RL5a appears to act as noncompetitive inhibitor of ORC with respect to ATP.

potent inhibitor of the replication licensing system.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3