SML3464

Gossypetin

≥98% (HPLC), MKK3 and MKK6 protein kinases inhibitor, powder

• Synonim(y): 2-(3,4-Dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-1-benzopyran-4-one, 8-Hydroxyquercetin, Articulatidin, Equisporol
• Wzór empiryczny (zapis Hilla): C₁₅H₁₀O₈
• Numer CAS: 489-35-0
• Masa cząsteczkowa: 318.24
• NACRES: NA.77
• UNSPSC Code: 12352200
• MDL number: MFCD00017680
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Nazwa produktu: Gossypetin, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: , light green to yellow
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C
• SMILES string: OC1=CC(O)=C2C(C(O)=C(OC2=C1O)C3=CC=C(C(O)=C3)O)=O
• InChI: 1S/C15H10O8/c16-6-2-1-5(3-7(6)17)14-13(22)12(21)10-8(18)4-9(19)11(20)15(10)23-14/h1-4,16-20,22H
• InChI key: YRRAGUMVDQQZIY-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

Antioxidant, antibacterial, anticancer; potent inhibitor of MKK3 and MKK6 protein kinases

Gossypetin is a hexahydroxylated flavonoid found in the flowers and the calyx of Hibiscus, which exhibits numerous pharmacological effects, including antioxidant, antibacterial and anticancer activities. It induces apoptosis and autophagic cell death in prostate cancer cells. Gossypetin is a potent inhibitor of MKK3 and MKK6 protein kinases that suppresses esophageal cancer growth.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable