SML3746

TFCH

≥98% (HPLC)

• Synonim(y): 7-Hydrazinyl-4-(trifluoromethyl)-2H-1-benzopyran-2-one
• Wzór empiryczny (zapis Hilla): C₁₀H₇F₃N₂O₂
• Numer CAS: 1397225-10-3
• Masa cząsteczkowa: 244.17
• UNSPSC Code: 12352200
• NACRES: NA.21
• MDL number: MFCD09999550
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: , Faint yellow to yellow brown
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C

Opis

Biochem/physiol Actions

Brain penetrant, photo-stable, hydrazinyl coumarin compound that acts as a two-photon highly selective fluorescent sensor for both malondialdehyde and formaldehyde

TFCH is a photo-stable, hydrazinyl coumarin compound that acts as a two-photon fluorescent sensor for biomolecule carbonyls with low biotoxicity and extraordinary biocompatibility. TFCH is blood-brain barrier permeant, highly selective for both malondialdehyde (MDA) and formaldehyde (FA) with low detection levels (0.13 & 0.11 uM), respectively. It is shown to simultaneously and separately detect and image MDA and FA (0.11 uM) levels in living brains (0.37 mg/kg, i.p.) and in PC12 cells by two-photon microscopy. TFCH efficiently detects modest forms of renal injury with much greater sensitivity than standard assays for nephrotoxins. For MDA: Ex 365 & 800 nm, Em 440 nm; For FA: Ex 365 & 800 nm, Em 510 nm.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• WGK: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable