SML4146

Galidesivir Hydrochloride

≥95% (HPLC)

• Synonim(y): (2S,3S,4R,5R)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)pyrrolidine-3,4-diol hydrochloride, Immucillin A hydrochloride, BCX4430 hydrochloride
• Wzór empiryczny (zapis Hilla): C₁₁H₁₅N₅O₃ · xHCl
• Masa cząsteczkowa: 265.27 (free base basis)
• UNSPSC Code: 12352203
• Assay: ≥95% (HPLC)
• Form: powder
• Storage condition: desiccated

Właściwości

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 2 mg/mL, clear
• storage temp.: -10 to -25°C

Opis

Biochem/physiol Actions

Galidesivir (BCX4430) is an inhibitor of viral RNA-dependent RNA polymerase (RDRP) function with broad spectrum antiviral activity including against West Nile virus and tick-borne flaviviruses, Zika, haemorrhagic filoviruses Ebola and Marburg in addition to bunyaviruses, arenaviruses, paramyxoviruses, and coronaviruses. Galidesivir potently inhibits SARS-CoV-2 replication in cell-based assays. Also, it protected against Ebola virus and Marburg virus disease in rodent models and protected macaques from Marburg virus infection when given as late as 48 hours after infection.

Disclaimer

Hygroscopic Store with desiccant

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable