SML4412

BMOE

≥98% (HPLC)

• Synonim(y): 1,2-Bismaleimidoethane; Bis-maleimidoethane; Ethylenebismaleimide; 1,1′-(1,2-Ethanediyl)bis[1H-pyrrole-2,5-dione], BMOE, Short-arm Cross-linker, Cross-linker BMOE
• Wzór empiryczny (zapis Hilla): C₁₀H₈N₂O₄
• Numer CAS: 5132-30-9
• Masa cząsteczkowa: 220.18
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C

Opis

Biochem/physiol Actions

BMOE is a membrane-permeable, rigid, irreversible homo-bifunctional cross-linker with a short spacer arm (~8 Å) that forms a stable covalent thioether bond at pH 6.5–7.5, inducing conformational changes in proteins. Bismaleimidoethane effectively targets bis-cysteines within a 6.3–10.5 Å distance, enabling near-stoichiometric cross-linking and facilitating the study of protein-protein interactions and complex architecture in native cellular environments. BMOE is particularly useful for probing the quaternary structure of proteins, exploring oligomerization, and characterizing disulfide bond formation in intact cells.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable