V0377

[Arg⁸]-Vasopressin solution

Grade VI (synthetic), ~100 IU/mL in 0.9% NaCl

• Synonim(y): β-Hypophamine, AVP, Antidiuretic hormone, Arginine vasopressin
• Wzór empiryczny (zapis Hilla): C₄₆H₆₅N₁₅O₁₂S₂
• Numer CAS: 113-79-1
• Masa cząsteczkowa: 1084.23
• NACRES: NA.32
• PubChem Substance ID: 24900692
• UNSPSC Code: 51111800
• MDL number: MFCD00076738
• Biological source: synthetic (organic)
• Form: liquid

Właściwości

• biological source: synthetic (organic)
• Quality Segment: 200
• sterility: non-sterile
• type: Grade VI (synthetic)
• form: liquid
• contains: 0.4% 4-chlorobutanol as preservative
• concentration: ~100 IU/mL in 0.9% NaCl
• pH: ~3.5
• UniProt accession no.: P01185
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: NC1CSSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc3ccc(O)cc3)NC1=O)C(=O)N4CCCC4C(=O)NC(CCCNC(N)=N)C(=O)NCC(N)=O
• InChI: 1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)
• InChI key: KBZOIRJILGZLEJ-UHFFFAOYSA-N
• Gene Information: human ... AVP(551)

Opis

Application

[Arg⁸]-Vasopressin solution was used as an antigen for preparing preadsorbed antisera for immunocytochemistry. The product was used in L6 cell culture of the C5 subclone for differentiation studies.

Biochem/physiol Actions

[Arg⁸]-Vasopressin solution also known as Antidiuretic hormone, Arginine vasopressin or beta-Hypophamine is a selective and potent vasopressor agent that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock. It stimulates three acid-base transporters and hence increases the capability of the cell to regulate pH.

Endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. Arg⁸-vasopressin is also a neurotransmitter in the central nervous system. It is implicated in a variety of physiological processes including diuresis, vasoregulation, and memory. Regulates water balance by antidiuretic action; contracts arterioles (vasopressor action).

Endogenous antidiuretic hormone in most mammalian species; neurotransmitter in the central nervous system implicated in a variety of physiological processes including diuresis, vasoregulation, and memory.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 10 - Combustible liquids
• Co się dzieje?: WGK 2
• Temperatura zapłonu (°F): 235.4 °F - closed cup
• Temperatura zapłonu (°C): 113 °C - closed cup