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Merck

Pharmacokinetics of the new progestogens and influence of gestodene and desogestrel on ethinylestradiol metabolism.

Contraception (1997-05-01)
F Z Stanczyk
ABSTRAKT

The purpose of the present report is to summarize the most important pharmacokinetic features of the new progestogens. In addition, the question of whether or not gestodene, in comparison to desogestrel, has an influence on the pharmacokinetics of ethinylestradiol (EE2) will be addressed.

MATERIAŁY
Numer produktu
Marka
Opis produktu

Ethinylestradiol, European Pharmacopoeia (EP) Reference Standard
Supelco
Ethinyl Estradiol, Pharmaceutical Secondary Standard; Certified Reference Material
USP
Etynyloestradiol, United States Pharmacopeia (USP) Reference Standard
Desogestrel, European Pharmacopoeia (EP) Reference Standard
Gestodene, European Pharmacopoeia (EP) Reference Standard
Supelco
17α-Ethynylestradiol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
Sigma-Aldrich
17α-Ethynylestradiol, ≥98%
Sigma-Aldrich
Gestodene, ≥98% (HPLC)
Desogestrel for system suitability, European Pharmacopoeia (EP) Reference Standard
Ethinylestradiol for system suitability, European Pharmacopoeia (EP) Reference Standard