SCN7A
sodium channel, voltage-gated, type VII, alpha subunit
同義詞:
NaG, Nav2.1, Nav2.2, SCN6A
物種:
Human SCN7A (6332), Mouse Scn7a (20272), Rat Scn7a (64155), naked mole-rat Scn7a (101711842), domestic guinea pig Scn7a (100715553), dog SCN7A (488382), Horse SCN7A (100062186), cow SCN7A (507516), sheep SCN7A (101109522), domestic cat SCN7A (101082080)
UniProtKB ID:
基因 ID:
- Human(6332) Summary: This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011]
- Mouse(20272) sodium channel, voltage-gated, type VII, alpha
- Rat(64155) sodium channel, voltage-gated, type VII, alpha
- naked mole-rat(101711842) sodium channel, voltage-gated, type VII, alpha subunit
- domestic guinea pig(100715553) sodium channel, voltage-gated, type VII, alpha subunit
- dog(488382) sodium channel, voltage-gated, type VII, alpha subunit
- Horse(100062186) sodium channel, voltage-gated, type VII, alpha subunit
- cow(507516) sodium channel, voltage-gated, type VII, alpha subunit
- sheep(101109522) sodium channel, voltage-gated, type VII, alpha subunit
- domestic cat(101082080) sodium channel, voltage-gated, type VII, alpha subunit
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