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Merck

WT1

Wilms tumor 1

同義詞:
AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33
物種:
Human WT1 (7490), Mouse Wt1 (22431), Rat Wt1 (24883), domestic guinea pig Wt1 (100716139), dog WT1 (609253), sheep WT1 (100101227), naked mole-rat Wt1 (101714640), cow WT1 (280959), chicken WT1 (396139), cow WT1 (782183) ...更多
UniProtKB ID:
P19544, A8K6S1, B3KSA5, Q15881, Q16256, Q16575, Q4VXV4, Q4VXV5
基因 ID:
  • Human(7490) Summary: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Oct 2010]
  • Mouse(22431) Wilms tumor 1 homolog
  • Rat(24883) Wilms tumor 1
  • domestic guinea pig(100716139) Wilms tumor 1
  • dog(609253) Wilms tumor 1
  • sheep(100101227) Wilms tumor 1
  • naked mole-rat(101714640) Wilms tumor 1
  • cow(280959) Wilms tumor 1
  • chicken(396139) Wilms tumor 1
  • cow(782183) Wilms tumor 1
  • cow(614584) Wilms tumor 1
  • domestic cat(101088518) Wilms tumor 1

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Antibodies

產品編號
描述
物種活性
應用
348M-9
WT1 (6F-H2) Mouse Monoclonal Antibody, ,
物種活性
human
應用
immunohistochemistry
05-753
抗-WT1抗体，克隆6F-H2, clone 6F-H2, Upstate®, from mouse,
物種活性
human
應用
immunocytochemistry
immunohistochemistry
western blot
MAB4234
抗-肾母细胞′瘤抗体，NT，克隆6F-H2, clone 6F-H2, Chemicon®, from mouse,
物種活性
human, mouse
應用
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB2102716
Anti-WT1 antibody produced in rabbit, affinity isolated antibody,
物種活性
human
應用
western blot
SAB1409796
Monoclonal Anti-WT1 antibody produced in mouse, clone 1E9, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunohistochemistry
western blot

Proteins

產品編號
描述
物種
SRP2083
WT-1 (-KTS) human, recombinant, expressed in insect cells, ≥60% (SDS-PAGE),
物種
human

esiRNA

產品編號
描述
物種
EHU083661
MISSION® esiRNA, targeting human WT1,
物種
human