MilliporeSigma

TLR7

toll-like receptor 7

Synonyms:
TLR7-like
Species:
UniProtKB ID:
Gene ID:
  • Human(51284) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]
  • Mouse(170743) toll-like receptor 7
  • Rat(317468) toll-like receptor 7
  • naked mole-rat(101705918) toll-like receptor 7
  • domestic guinea pig(100713329) toll-like receptor 7
  • cow(493686) toll-like receptor 7
  • Horse(791248) toll-like receptor 7
  • sheep(554254) toll-like receptor 7
  • Goat(100860934) toll-like receptor 7
  • dog(491743) toll-like receptor 7
  • Zebrafish(100534776) toll-like receptor 7
  • chicken(418638) toll-like receptor 7
  • domestic cat(493685) toll-like receptor 7

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Product Number
Description
Species
Imiquimod, United States Pharmacopeia (USP) Reference Standard,
Species
human
Imiquimod, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
2-((4-(7-Chloroquinolin-4-ylamino)pentyl)(ethyl)amino)ethanol, ,
Species
human
2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol, British Pharmacopoeia (BP) Reference Standard,
Species
human
Hydroxychloroquine sulfate, ≥98% (HPLC), powder,
Species
human
Hydroxychloroquine sulfate, British Pharmacopoeia (BP) Reference Standard,
Species
human
Hydroxychloroquine sulfate, analytical standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TLR7 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry

western blot
Anti-TLR7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-TLR7 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-TLR7 Mouse mAb (2C9), liquid, clone 2C9, Calbiochem®,
Species Reactivity
human
Application
Anti-TLR7 Antibody, clone 3G6S4, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
PrEST Antigen TLR7, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Tlr7,
Species
mouse
MISSION® esiRNA, targeting human TLR7,
Species
human