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CCL2

chemokine (C-C motif) ligand 2

Synonyms:
GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF
Species:
UniProtKB ID:
Gene ID:
  • Human(6347) Summary: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2008]
  • Mouse(20296) chemokine (C-C motif) ligand 2
  • Rat(24770) chemokine (C-C motif) ligand 2
  • dog(403981) chemokine (C-C motif) ligand 2
  • naked mole-rat(101697988) chemokine (C-C motif) ligand 2
  • Domestic Rabbit(100009130) chemokine (C-C motif) ligand 2
  • domestic guinea pig(100135494) chemokine (C-C motif) ligand 2
  • Horse(100034136) chemokine (C-C motif) ligand 2
  • cow(281043) chemokine (C-C motif) ligand 2
  • sheep(101120093) chemokine (C-C motif) ligand 2
  • sheep(100294591) chemokine (C-C motif) ligand 2

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ELISA

Product Number
Description
Species
Bovine MCP-1 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
cow
Rat MCP-1 / CCL2 ELISA Kit, for cell and tissue lysates,
Species
rat
Rat MCP-1 / CCL2 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
rat
Mouse MCP-1 / CCL2 ELISA Kit, for cell and tissue lysates,
Species
mouse
Mouse MCP-1 / CCL2 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-Monocyte Chemotactic Protein-1 antibody produced in mouse, clone 24822, purified immunoglobulin, lyophilized powder,
Species Reactivity
human
Application
neutralization
western blot
Anti-MCP-1 Antibody, clone 2G17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunofluorescence

immunohistochemistry

western blot
Anti-CCL2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-CCL2 antibody produced in mouse, clone 2E2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Human MCP-1 Conferma® ELISA, quantification of human MCP-1 in serum, plasma, or culture media samples.,
Species Reactivity
human
Application
ELISA

Proteins

Product Number
Description
Species
MCP-1/MCAF human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
JE/MCP-1 (CCL2) from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse
SILuLite CCL2 C-C motif chemokine 2 human, recombinant, expressed in HEK 293 cells, MS Protein Standard,
Species
human
SILuProt CCL2 C-C motif chemokine 2 human, SIL MS Protein Standard, 13C and 15N-labeled,
Species
human
Monocyte Chemotactic Protein-1 human, ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CCL2,
Species
human
MISSION® esiRNA, targeting mouse Ccl2,
Species
mouse