MilliporeSigma

PDGFB

platelet-derived growth factor beta polypeptide

Synonyms:
PDGF-2, PDGF2, SIS, SSV, c-sis
Species:
UniProtKB ID:
Gene ID:
  • Human(5155) Summary: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2013]
  • Mouse(18591) platelet derived growth factor, B polypeptide
  • Rat(24628) platelet-derived growth factor beta polypeptide
  • naked mole-rat(101698830) platelet-derived growth factor beta polypeptide
  • dog(442986) platelet-derived growth factor beta polypeptide
  • sheep(443545) platelet-derived growth factor beta polypeptide
  • domestic guinea pig(100731469) platelet-derived growth factor beta polypeptide
  • cow(540106) platelet-derived growth factor beta polypeptide
  • chicken(374128) platelet-derived growth factor beta polypeptide
  • Zebrafish(565324) platelet derived growth factor, B polypeptide

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ELISA

Product Number
Description
Species
Porcine PDGFB / Platelet-derived Growth Factor Subunit B ELISA Kit, ,
Species
Canine PDGFB / Platelet-derived Growth Factor Subunit B ELISA Kit, ,
Species
dog
Human PDGF-BB ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Human PDGF-BB ELISA Kit, for cell and tissue lysates,
Species
human
Rhesus Macaque PDGF-BB ELISA, for serum, plasma and cell culture supernatants,
Species

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PDGF-BB Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
ELISA
neutralization

western blot
Anti-PDGF-BB Antibody, clone 6A9.9.11, ,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Platelet-Derived Growth Factor-BB antibody produced in goat, affinity isolated antibody, lyophilized powder,
Species Reactivity
human
Application
neutralization
western blot
Anti-PDGFB antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-PDGFB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
Platelet-Derived Growth Factor-BB human, PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
human
Platelet-Derived Growth Factor-BB from rat, PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
rat
Platelet-Derived Growth Factor-BB human, PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
human
PDGF-BB from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse
PDGF-BB human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PDGFB,
Species
human