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SRC

v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

Synonyms:
ASV, SRC1, c-SRC, p60-Src
Species:
UniProtKB ID:
Gene ID:
  • Human(6714) Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20779) Rous sarcoma oncogene
  • Rat(83805) v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • Zebrafish(325084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • chicken(396442) v-src sarcoma viral oncogene
  • domestic cat(101100378) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • dog(485864) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • sheep(101103084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • cow(535742) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • domestic guinea pig(100728509) Rous sarcoma oncogene
  • naked mole-rat(101703827) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

Custom & Knockdown Gene Products

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Small Molecule - Antagonist

Product Number
Description
Species
Phosphoric acid, crystalline, ≥99.999% trace metals basis,
Species
human
Malonic acid, ReagentPlus®, 99%,
Species
human
Oxalic acid, purified grade, 99.999% trace metals basis,
Species
human
Oxalic acid, puriss. p.a., anhydrous, ≥99.0% (RT),
Species
human
Oxalic acid, ReagentPlus®, ≥99%,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SRC antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, human, mouse, rabbit, rat
Application
western blot
Anti-SRC, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-SRC, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-SRC (Ab-529) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-SRC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
SU 6656, ≥98% (HPLC),
Species
human
Radicicol from Diheterospora chlamydosporia, solid,
Species
human, rat
Ellagic acid, ≥95% (HPLC), powder, from tree bark,
Species
human, rat
Tyrphostin A9, solid,
Species
mouse, human
Dasatinib, ,
Species
human

Kits

Product Number
Description
Species
Src Kinase Reaction Buffer, ,
Species
human

Proteins

Product Number
Description
Species
Src (1-530) Protein, active, 10 µg, ,
Species
human
Src Manganese/ATP Cocktail, ,
Species
human
Src (T341M) Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation. For use in Kinase Assays.,
Species
human
Src human, ≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution, histidine-tagged,
Species
human
Src Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, full-length, human Src. For use in Kinase Assays.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Src,
Species
mouse

Small Molecule - Substrate

Product Number
Description
Species
Src Substrate Peptide, Src Substrate Peptide primarily used in Kinase Assays.,
Species
human