R1908

Remifentanil hydrochloride

≥97% (HPLC), powder

• Synonym(s): 3-[methoxycarbonyl-4-[(1-oxopropyl)phenylamino]1-piperidine]propanoic acid methyl ester hydrochloride, GI-87084B, Remifentanyl, Ultiva
• Empirical Formula (Hill Notation): C₂₀H₂₈N₂O₅·HCl
• CAS Number: 132539-07-2
• Molecular Weight: 412.91
• MDL number: MFCD00910882
• PubChem Substance ID: 329824010

Properties

• Quality Level: 100
• Assay: ≥97% (HPLC)
• form: powder
• drug control: USDEA Schedule II; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• color: white to off-white
• solubility: H₂O: ≥20 mg/mL
• storage temp.: 2-8°C
• SMILES string: O=C(CC)N(C1(CCN(CCC(OC)=O)CC1)C(OC)=O)C2=CC=CC=C2.[H]Cl
• InChI: 1S/C20H28N2O5.ClH/c1-4-17(23)22(16-8-6-5-7-9-16)20(19(25)27-3)11-14-21(15-12-20)13-10-18(24)26-2;/h5-9H,4,10-15H2,1-3H3;1H
• InChI key: WFBMIPUMYUHANP-UHFFFAOYSA-N
• Gene Information: human ... OPRM1(4988)

Description

Biochem/physiol Actions

Remifentanil hydrochloride is a mu opioid receptor agonist, anesthetic, and analgesic compound. Remifentanil was developed as an ultra-short-acting mu opioid receptor agonist with improved pharmacodynamic properties.

Features and Benefits

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H371
• Precautionary Statements: P260 - P264 - P270 - P308 + P311 - P405 - P501
• Hazard Classifications: STOT SE 2
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable