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2011

Bilirubin

solid, bile pigment, Calbiochem®

Sinónimos:

Bilirubin

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A ustedes/SKUDisponibilidadPrecio
1 g
Comprobar disponibilidad del carrito
$276.00

Acerca de este artículo

Fórmula empírica (notación de Hill):
C33H36N4O6
Número CAS:
Peso molecular:
584.66
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Form:
solid
Storage condition:
OK to freeze, protect from light

$276.00


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Nombre del producto

Bilirubin, Principal pigment of bile and one of the major end products of hemoglobin decomposition.

Quality Segment

description

RTECS - DU3038000
Merck USA index - 14, 1218

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

red-brown

solubility

chloroform: 1 mg/mL, alkaline solution: soluble

shipped in

ambient

storage temp.

10-30°C

SMILES string

[nH]1c(c(c(c1\C=C4/NC(=O)C(=C/4C)C=C)C)CCC(=O)O)Cc2[nH]c(c(c2CCC(=O)O)C)\C=C3/NC(=O)C(=C/3C=C)C

InChI

1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-

InChI key

BPYKTIZUTYGOLE-IFADSCNNSA-N

General description

Bilirubin is an orange-yellow bile pigment and one of the major end products of hemoglobin decomposition. It contains conjugated double bonds and reactive hydrogen atoms. In adults, the upper limit of the normal range of bilirubin is >1mg/dL. Serum levels of bilirubin in healthy newborns are less than 15 mg/dl. This product corresponds to the unconjugated form.

Biochem/physiol Actions

Bilirubin is reported to cross the blood-brain barrier and exert significant antioxidant effects in the brain. This pigment aids in coloration in the various forms of jaundice. Bilirubin levels act as biomarkers in liver and blood disorders. Unconjugated form of bilirubin at lower levels serves as a physiological antioxidant. However, increased concentration of bilirubin is toxic and leads to neonatal hyperbilirubinemia in neonates.

Preparation Note

Unstable in basic solutions; reconstitute just prior to use.

Other Notes

Extinction coefficient (454 nm, CHCl3):59,100-62,300 M-1cm-1.
Cell permeable: no
Reversible: no
Product does not compete with ATP.
Primary Target

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Este artículo
B4126NIST916B201102
Bilirrubina NIST®SRM®

NIST916B

Bilirrubina

description

Principal pigment of bile and one of the major end products of hemoglobin decomposition.

description

≥98% (EmM/453 = 60), powder

description

NIST®SRM®

description

Bilirubin Conjugate, Ditaurate, Disodium Salt is suitable as a direct bilirubin standard. Behaves similar to purified bilirubin glucuronides from human bile in diazo tests. Unstable in solution.

form

solid

form

powder

form

-

form

solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

NIST®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

300

Quality Level

-

Quality Level

100

storage temp.

10-30°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage condition

protect from light, OK to freeze

storage condition

-

storage condition

-

storage condition

protect from light, desiccated (hygroscopic), OK to freeze

solubility

alkaline solution: soluble, chloroform: 1 mg/mL

solubility

chloroform: soluble, benzene: soluble, aqueous base: soluble, aqueous acid: soluble

solubility

-

solubility

water: 10 mg/mL


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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