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ABD136

Anti-LGI1 Antibody

from rabbit, purified by affinity chromatography

Sinónimos:

Leucine-rich glioma inactivated protein 1, Epitempin-1

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Talla/SKUDisponibilidadPrecio
100 μg
Comprobar disponibilidad del carrito
$432.00

Acerca de este artículo

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
-

$432.00


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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

species reactivity (predicted by homology)

human (immunogen homology)

technique(s)

western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... LGI1(9211)

General description

Leucine-rich glioma inactivated gene 1 (LGI1), also known as Epitempin-1 (EPT), is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) regulating voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. LGI1 may play a role in the control of neuroblastoma cell survival and may play a role in other cancers. It is expressed in neural tissue, especially brain. Mutations in LGI1 have been associated with nearly half of autodominant lateral temporal epilepsy (ADTLE).
~56 kDa observed. Uniprot describes 3 isoforms at ~33 kDa, ~58 kDa, and ~64 kDa Uncharacterized bands may appear in some lysates.

Immunogen

KLH-conjugated linear peptide corresponding to the N-terminus of human LGI1.

Application

Detect LGI1 using this rabbit polyclonal antibody, Anti-LGI1 Antibody validated for use in western blotting.

Biochem/physiol Actions

This antibody recognizes the N-terminus of LGI1.

Analysis Note

Evaluated by Western Blotting/Peptide Inhibition Assay in mouse brain tissue lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected LGI1 in 15 µg of mouse brain tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Este artículo
PRS4489ABN351ABN347
description

from rabbit, purified by affinity chromatography

description

affinity isolated antibody, buffered aqueous solution

description

from rabbit, purified by affinity chromatography

description

from rabbit, purified by affinity chromatography

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

technique(s)

western blot: suitable

technique(s)

indirect ELISA: suitable, western blot: suitable, immunofluorescence: suitable, immunohistochemistry: suitable

technique(s)

western blot: suitable

technique(s)

western blot: suitable

Gene Information

human ... LGI1(9211)

Gene Information

human ... LGI1(9211)

Gene Information

human ... LGI3(203190)

Gene Information

human ... LGI4(163175)


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Clase de almacenamiento

12 - Non Combustible Liquids

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Certificados de análisis (COA)

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