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08511

Curcumin

analytical standard

Oferta disponible

Sinónimos:

(E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane, Diferulylmethane, Natural Yellow 3

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Talla/SKUDisponibilidadPrecio
10 mg
Comprobar disponibilidad del carrito
$251.00

Acerca de este artículo

Fórmula lineal:
[HOC6H3(OCH3)CH=CHCO]2CH2
Número CAS:
Peso molecular:
368.38
UNSPSC Code:
85151701
NACRES:
NA.24
E Number:
E100
PubChem Substance ID:
EC Number:
207-280-5
MDL number:
Colour Index Number:
75300
Beilstein/REAXYS Number:
2306965

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grade

analytical standard

Quality Segment

vapor density

13 (vs air)

assay

≥98.0% (HPLC)

form

powder

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O

InChI

1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+

InChI key

VFLDPWHFBUODDF-FCXRPNKRSA-N

General description

Curcumin is an anti-inflammatory agent extracted from the roots of Curcuma longa Linn.

Application

Curcumin may be used as a reference standard for the determination of curcumin in rat plasma by high-performance liquid chromatography method.

Biochem/physiol Actions

A natural phenolic compound responsible for the yellow color of turmeric. Potent anti-tumor agent that acts against highly diverse tumor-specific pathways. Anti-inflammatory and anti-oxidant. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cyclooxygenase (COX-2) and 5-lipoxygenase (5-LOX).
A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Curcumin has been cited as a potential chemopreventive agent, in addition to its chemotherapeutic activity. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: curcuma

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Este artículo
C1386C77271151855
Curcumin United States Pharmacopeia (USP) Reference Standard

USP

1151855

Curcumin

description

analytical standard

description

from Curcuma longa (Turmeric), powder

description

≥94% (curcuminoid content), ≥80% (Curcumin)

description

United States Pharmacopeia (USP) Reference Standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

grade

analytical standard

grade

-

grade

-

grade

pharmaceutical primary standard

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

pharmaceutical (small molecule)

assay

≥98.0% (HPLC)

assay

-

assay

≥94% (curcuminoid content), ≥80% (Curcumin)

assay

-

format

neat

format

-

format

-

format

neat

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-


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Clase de almacenamiento

11 - Combustible Solids

¿Qué está pasando?

WGK 3

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)

Not applicable



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Questions

  1. Good morning, do you know the solubility of curcumin in 70% ethanol and absolute ethanol? Thank you in advance.

    1 answer
    1. Curcumin is generally more soluble in pure ethanol. Ethanol's ability to dissolve curcumin is enhanced due to non-polar characteristics, which can effectively interact with the non-polar regions of curcumin. While curcumin is soluble in 70% ethanol, solubility is typically lower than in 100% ethanol.

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