B134

BMY 7378 dihydrochloride

≥98% (HPLC), solid

• Sinónimos: 8-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione dihydrochloride
• Fórmula empírica (notación de Hill): C₂₂H₃₁N₃O₃ · 2HCl
• Número CAS: 21102-95-4
• Peso molecular: 458.42
• NACRES: NA.77
• PubChem Substance ID: 24278080
• UNSPSC Code: 12352200
• MDL number: MFCD00153771
• Assay: ≥98% (HPLC)
• Form: solid

Propiedades

• assay: ≥98% (HPLC)
• form: solid
• color: white
• solubility: H₂O: >5 mg/mL
• SMILES string: Cl.Cl.COc1ccccc1N2CCN(CC2)CCN3C(=O)CC4(CCCC4)CC3=O
• InChI: 1S/C22H31N3O3.2ClH/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22;;/h2-3,6-7H,4-5,8-17H2,1H3;2*1H
• InChI key: NIBOMXUDFLRHRV-UHFFFAOYSA-N
• Gene Information: human ... ADRA1D(146), HTR1A(3350)

Descripción

Biochem/physiol Actions

BMY 7378 dihydrochloride is a partial 5-HT_1A serotonin receptor agonist and selective α_1D-adrenoceptor antagonist.

Features and Benefits

This compound is featured on the α1-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

Manufactured and sold with the permission of Bristol Myers Squibb Corporation.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): Eyeshields, Gloves, type N95 (US)