D6000

2′-Deoxyadenosine 5′-di­phos­phate sodium salt

≥95% (HPLC), synthetic (organic), powder

• Sinónimos: dADP
• Fórmula empírica (notación de Hill): C₁₀H₁₅N₅O₉P₂ · xNa⁺
• Número CAS: 72003-83-9
• Peso molecular: 411.20 (free acid basis)
• NACRES: NA.51
• PubChem Substance ID: 24893990
• UNSPSC Code: 41106305
• EC Number: 276-280-5
• MDL number: MFCD00083610
• Assay: ≥95% (HPLC)
• Biological source: synthetic (organic)
• Form: powder
• Storage temp.: −20°C

Propiedades

• Nombre del producto: 2′-Deoxyadenosine 5′-di­phos­phate sodium salt,
• biological source: synthetic (organic)
• Quality Segment: 200
• assay: ≥95% (HPLC)
• form: powder
• storage temp.: −20°C
• SMILES string: [Na].Nc1ncnc2n(cnc12)C3CC(O)C(COP(O)(=O)OP(O)(O)=O)O3
• InChI: 1S/C10H15N5O9P2.Na.H/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(23-7)2-22-26(20,21)24-25(17,18)19;;/h3-7,16H,1-2H2,(H,20,21)(H2,11,12,13)(H2,17,18,19);;
• InChI key: KZGAPWRJMWSNQO-UHFFFAOYSA-N

Descripción

General description

2′-Deoxyadenosine5′-di­phos­phate (dADP) is a purine containing adenine as the nucleobase. It isproduced as a product of hypoxanthine oxidase action on hypoxanthine duringpurine degradation in the body.

Application

2′-Deoxyadenosine 5′-diphosphate (dADP) may be used for the synthesis of deoxyadenylate oligonucleotides with enzymes such as polynucleotide phosphorylase from Escherichia coli. dADP is used as an inhibitor of bacterial poly(A) polymerase. DeoxyADP may be use as an alternative substrate or inhibitor for studies of ATPase and DNA and RNA polymerase specificity.

Información de seguridad

• Pictogramas: GHS06
• Palabra de advertencia: Danger
• Códigos de peligro: H301 + H311 + H331,H315,H319,H335
• Indicaciones de precaución: P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos diana: Respiratory system
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• ¿Qué está pasando?: WGK 3
• EPI (equipos de protección individual): Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges