This product is tested for suitability in HPLC. The minimum purity of this material is 97%, and the maximum water content is 2.0 mol. These values are lot-specific and reported in the Certificate of Analysis. This material is not tested for use as an analytical standard. Suitability for this application would have to be determined by the end user. Please see the link below to review a sample or lot specific Certificate:
https://www.sigmaaldrich.com/product/sigma/p1499#product-documentation
P1499
Pterostilbene
≥97% (HPLC), apoptosis inducer, solid
Oferta disponible
Sinónimos:
Pterocarpus marsupium, 3,5-Dimethoxy-4′-hydroxystilbene, 4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol
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| Talla/SKU | Disponibilidad | Precio |
|---|---|---|
10 mg | Disponible para enviar HOYdesdeMILWAUKEE | $340.00 |
Acerca de este artículo
Fórmula empírica (notación de Hill):
C16H16O3
Número CAS:
Peso molecular:
256.30
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥97% (HPLC)
Form:
solid
Storage condition:
protect from light
Servicio técnico
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Permítanos ayudarleNombre del producto
Pterostilbene, ≥97% (HPLC), solid
Quality Segment
assay
≥97% (HPLC)
form
solid
storage condition
protect from light
solubility
DMSO: >20 mg/mL, H2O: insoluble
storage temp.
2-8°C
SMILES string
COc1cc(OC)cc(\C=C\c2ccc(O)cc2)c1
InChI
1S/C16H16O3/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11,17H,1-2H3/b4-3+
InChI key
VLEUZFDZJKSGMX-ONEGZZNKSA-N
General description
Application
Pterostilbene has been used:
- to investigate its anti-oxidative stress activities and the involvement of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-antioxidant response element (ARE) signaling pathway
- to determine its effects on transcriptional activation of estrogen receptor-α (ERα) in hormone resistant breast cancer cells)
- to study its effects on the cytotoxicity of 2-chloroethyl ethyl sulphide (CEES) in human epidermoid carcinoma cells (A-431) through MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide)viability assay
Biochem/physiol Actions
Pterostilbene exhibits antineoplastic properties in some of the malignancies, hence it is considered as an active anticancer agent. It has the ability to stimulate apoptosis and block the viability of cell in estrogen-receptor positive and negative breast cancer cell lines.
Antioxidant, antiproliferative, apoptosis inducer, antihyperglycemic, antidiabetic.
Disclaimer
Air-sensitive
1 of 1
Este artículo | |||
|---|---|---|---|
| description ≥97% (HPLC), solid | description A cell-permeable methoxylated analog of Resveratrol that displays antioxidant, antiproliferative, and hypoglycemic properties. | description ≥98% (HPLC) | description - |
| form solid | form solid | form powder | form powder |
| assay ≥97% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. room temp |
| solubility H2O: insoluble, DMSO: >20 mg/mL | solubility DMSO: 10 mg/mL, methanol: 10 mg/mL | solubility DMSO: 3 mg/mL, clear (warmed) | solubility DMSO: ≥20 mg/mL |
| storage condition protect from light | storage condition protect from light, OK to freeze | storage condition - | storage condition - |
Palabra de advertencia
Danger
Códigos de peligro
Indicaciones de precaución
Hazard Classifications
Aquatic Chronic 2 - Eye Dam. 1
Clase de almacenamiento
11 - Combustible Solids
¿Qué está pasando?
WGK 3
Punto de inflamación (°F)
Not applicable
Punto de inflamación (°C)
Not applicable
EPI (equipos de protección individual)
dust mask type N95 (US), Eyeshields, Gloves
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Actually we are using as a Analytical Standard for HPLC assay of Pterostilbene in RM and Final Product .Can we use this? if we can use How much purity we have to take for Calculation
1 answer-
Helpful?
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